Human B7-H2/ICOSLG/CD275 protein (Recombinant) (C-His) (STJP002721)

SKU:
STJP002721

£89.50 - £298.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human B7-H2/ICOSLG/CD275-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human B7-H2/ICOSLG at 1 Mu g/mL (100 Mu L/well) can bind Human ICOS/CD278 with a linear range of 2-14.8 ng/mL.
Gene Symbol: ICOSLG
Gene ID: 23308
Uniprot ID: ICOSL_HUMAN
Immunogen Region: Asp19-Ser258
Immunogen: Recombinant Human B7-H2/ICOSLG/CD275 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp19-Ser258) of human B7-H2/ICOSLG (Accession #NP_056074.1) fused with a 6×His tag at the C-terminus.
Function Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion.induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Protein Name Icos Ligand
B7 Homolog 2
B7-H2
B7-Like Protein Gl50
B7-Related Protein 1
B7rp-1
Cd Antigen Cd275
Database Links Reactome: R-HSA-388841
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Icos Ligand protein
B7 Homolog 2 protein
B7-H2 protein
B7-Like Protein Gl50 protein
B7-Related Protein 1 protein
B7rp-1 protein
Cd Antigen Cd275 protein
ICOSLG protein
B7H2 protein
B7RP1 protein
ICOSL protein
KIAA0653 protein

Information sourced from Uniprot.org

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