| Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. |
| Protein Name | Atp Synthase Subunit O - MitochondrialAtp Synthase Peripheral Stalk Subunit OscpOligomycin Sensitivity Conferral ProteinOscp |
| Database Links | Reactome: R-HSA-163210Reactome: R-HSA-8949613Reactome: R-HSA-9837999 |
| Cellular Localisation | MitochondrionMitochondrion Inner Membrane |
| Alternative Protein Names | Atp Synthase Subunit O - Mitochondrial proteinAtp Synthase Peripheral Stalk Subunit Oscp proteinOligomycin Sensitivity Conferral Protein proteinOscp proteinATP5PO proteinATP5O proteinATPO protein |
Information sourced from Uniprot.org
