Human ANKRD2 protein (Recombinant) (N-His) (STJP007659)

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STJP007659
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ANKRD2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ANKRD2
Gene ID: 26287
Uniprot ID: ANKR2_HUMAN
Immunogen Region: Asp148-His333
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylation at Ser-99 by PKB/AKT2 in response to oxidative stress induces translocation to the nucleus and negatively regulates myoblast differentiation.
Function Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress.
Protein Name Ankyrin Repeat Domain-Containing Protein 2
Skeletal Muscle Ankyrin Repeat Protein
Harpp
Cellular Localisation Cytoplasm
Myofibril
Sarcomere
I Band
Cytosol
Nucleus
Pml Body
In The Sarcoplasm Of Differentiated Striated Muscle Cells
Where It Is Cytosolic And Enriched In The I Band
In Nucleus And Pml Bodies Of Proliferating And Undifferentiated Myoblasts
Associates With The Euchromatin In The Nucleus Of Myocytes Upon Muscle Stress
Alternative Protein Names Ankyrin Repeat Domain-Containing Protein 2 protein
Skeletal Muscle Ankyrin Repeat Protein protein
Harpp protein
ANKRD2 protein
ARPP protein

Information sourced from Uniprot.org

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