Human Aldehyde Dehydrogenase 3-A1/ALDH3A1 protein (Recombinant) (His-Tag) (STJP016614)

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STJP016614
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Short Description :Recombinant-Human Aldehyde Dehydrogenase 3-A1/ALDH3A1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Enzyme Activity
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.1M NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Immunoreactivity:Specific activity is > 5, 000pmol/min/ug, and is defined as the amount of enzyme that catalyze the oxidation of 1.0 pmole 4-nitrobenzaldehyde by NADP per minute at pH 9.0 at 37 °C.
Gene Symbol:ALDH3A1
Gene ID:218
Uniprot ID:AL3A1_HUMAN
Accession Number:AAH04370.1
Immunogen:Human
Immunogen Region:1-453aa
Immunogen Sequence: MSKISEAVKR ARAAFSSGRT RPLQFRIQQL EALQRLIQEQ EQELVGALAA DLHKNEWNAY YEEVVYVLEE IEYMIQKLPE WAADEPVEKT PQTQQDELYI HSEPLGVVLV IGTWNYPFNL TIQPMVGAIA AGNAVVLKPS ELSENMASLL ATIIPQYLDK DLYPVINGGV PETTELLKER FDHILYTGST GVGKIIMTAA AKHLTP
Tissue Specificity High levels in stomach, esophagus and lung.low level in the liver and kidney.
Function ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids. Preferentially oxidizes aromatic aldehyde substrates. Comprises about 50 percent of corneal epithelial soluble proteins. May play a role in preventing corneal damage caused by ultraviolet light.
Protein Name Aldehyde Dehydrogenase - Dimeric Nadp-Preferring
Aldhiii
Aldehyde Dehydrogenase 3
Aldehyde Dehydrogenase Family 3 Member A1
Database Links Reactome: R-HSA-211945
Cellular Localisation Cytoplasm
Alternative Protein Names Aldehyde Dehydrogenase - Dimeric Nadp-Preferring protein
Aldhiii protein
Aldehyde Dehydrogenase 3 protein
Aldehyde Dehydrogenase Family 3 Member A1 protein
ALDH3A1 protein
ALDH3 protein

Information sourced from Uniprot.org

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