Human AEBP1 (AE Binding Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013347)
SPECIFICATIONS
General Information
| Short Description | This AEBP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.126ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | AEBP1 |
| Gene ID | 165 |
| Uniprot ID | AEBP1_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in osteoblast and visceral fat. |
| Post Translational Modifications | Phosphorylated by MAPK1 in vitro. |
| Function | Isoform 1: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix. Isoform 2: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. |
| Protein Name | Adipocyte Enhancer-Binding Protein 1Ae-Binding Protein 1Aortic Carboxypeptidase-Like Protein |
| Database Links | |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmNucleus |
| Alternative ELISA Names | Adipocyte Enhancer-Binding Protein 1 ELISA kitAe-Binding Protein 1 ELISA kitAortic Carboxypeptidase-Like Protein ELISA kitAEBP1 ELISA kitACLP ELISA kit |
| output |
Information sourced from Uniprot.org