Human ABO protein (Recombinant-Active) (N-His) (STJP011890)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human ABO-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its ability to transfer galactose from UDPgalactose to lactoN-fucopentaose. The specific activity is >1, 250 pmol/min/Mu g, as measured under the described conditions. |
Target Information
| Gene Symbol | ABO |
| Gene ID | 28 |
| Uniprot ID | BGAT_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg63-Pro354 |
Additional Info
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Glycosyltransferase that catalyzes the transfer of carbohydrates to H antigen, forming the antigenic structures of the ABO blood group. |
| Protein Name | Histo-Blood Group Abo System TransferaseFucosylglycoprotein 3-Alpha-GalactosyltransferaseFucosylglycoprotein Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-GalactosyltransferaseHisto-Blood Group A TransferaseA TransferaseHisto-Blood Group B TransferaseB TransferaseNagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form |
| Database Links | Reactome: R-HSA-9033807 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecretedMembrane-Bound Form In Trans Cisternae Of GolgiSecreted Into The Body Fluid |
| Alternative Protein Names | Histo-Blood Group Abo System Transferase proteinFucosylglycoprotein 3-Alpha-Galactosyltransferase proteinFucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase proteinGlycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase proteinGlycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase proteinHisto-Blood Group A Transferase proteinA Transferase proteinHisto-Blood Group B Transferase proteinB Transferase proteinNagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form proteinABO protein |
Information sourced from Uniprot.org