Human 17 beta-HSD14/HSD17B14 protein (Recombinant) (His-Tag) (STJP016937)

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STJP016937
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Short Description :Recombinant-Human 17 beta-HSD14/HSD17B14-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:HSD17B14
Gene ID:51171
Uniprot ID:DHB14_HUMAN
Accession Number:NP_057330
Immunogen:Human
Immunogen Region:1-270aa
Immunogen Sequence:MATG TRYAGKVVVV TGGGRGIGAG IVRAFVNSGA RVVICDKDES GGRALEQELP GAVFILCDVT QEDDVKTLVS ETIRRFGRLD CVVNNAGHHP PPQRPEETSA QGFRQLLELN LLGTYTLTKL ALPYLRKSQG NVINISSLVG AIGQAQAVPY VATKGAVTAM TKALALDESP YGVRVNCISP GNIWTP
Tissue Specificity Highly expressed in brain, placenta, liver and kidney.
Function Catalyzes the NAD(+)-dependent oxidation of L-fucose, yielding L-fucono-1,5-lactone, which rapidly converts spontaneously to L-fucone-1,4-lactone. Can also act on D-arabinose and L-galactose, with lower catalytic efficiency. Does not use NADPH. May be the initial enzyme of the L-fucose degradation pathway in mammals.
Protein Name L-Fucose Dehydrogenase
17-Beta-Hydroxysteroid Dehydrogenase Dhrs10
Dehydrogenase/Reductase Sdr Family Member 10
Retinal Short-Chain Dehydrogenase/Reductase Retsdr3
Short Chain Dehydrogenase/Reductase Family 47c Member 1
Database Links Reactome: R-HSA-193144
Cellular Localisation Cytoplasm
Alternative Protein Names L-Fucose Dehydrogenase protein
17-Beta-Hydroxysteroid Dehydrogenase Dhrs10 protein
Dehydrogenase/Reductase Sdr Family Member 10 protein
Retinal Short-Chain Dehydrogenase/Reductase Retsdr3 protein
Short Chain Dehydrogenase/Reductase Family 47c Member 1 protein
HSD17B14 protein
DHRS10 protein
SDR3 protein
SDR47C1 protein
UNQ502 protein
PRO474 protein

Information sourced from Uniprot.org

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