Human 17 beta-HSD1/HSD17B1 protein (Recombinant) (His-Tag) (STJP018208)

SKU:
STJP018208
£134.50 - £738.50
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Short Description :Recombinant-Human 17 beta-HSD1/HSD17B1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:HSD17B1
Gene ID:3292
Uniprot ID:DHB1_HUMAN
Accession Number:NP_000404
Immunogen:Human
Immunogen Region:1-328aa
Immunogen Sequence:MARTVV LITGCSSGIG LHLAVRLASD PSQSFKVYAT LRDLKTQGRL WEAARALACP PGSLETLQLD VRDSKSVAAA RERVTEGRVD VLVCNAGLGL LGPLEALGED AVASVLDVNV VGTVRMLQAF LPDMKRRGSG RVLVTGSVGG LMGLPFNDVY CASKFALEGL CESLAVLLLP FGVHLSLIEC GPVHTAFMEK VLGSPE
Function Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2). Also has 20-alpha-HSD activity. Uses preferentially NADH.
Protein Name 17-Beta-Hydroxysteroid Dehydrogenase Type 1
17-Beta-Hsd 1
20 Alpha-Hydroxysteroid Dehydrogenase
20-Alpha-Hsd
E2dh
Estradiol 17-Beta-Dehydrogenase 1
Placental 17-Beta-Hydroxysteroid Dehydrogenase
Short Chain Dehydrogenase/Reductase Family 28c Member 1
Database Links Reactome: R-HSA-193144
Reactome: R-HSA-2453902
Cellular Localisation Cytoplasm
Alternative Protein Names 17-Beta-Hydroxysteroid Dehydrogenase Type 1 protein
17-Beta-Hsd 1 protein
20 Alpha-Hydroxysteroid Dehydrogenase protein
20-Alpha-Hsd protein
E2dh protein
Estradiol 17-Beta-Dehydrogenase 1 protein
Placental 17-Beta-Hydroxysteroid Dehydrogenase protein
Short Chain Dehydrogenase/Reductase Family 28c Member 1 protein
HSD17B1 protein
E17KSR protein
EDH17B1 protein
EDH17B2 protein
EDHB17 protein
SDR28C1 protein

Information sourced from Uniprot.org