| Tissue Specificity | In embryo, expressed in endoderm layer of yolk sac and liver primordium. |
| Post Translational Modifications | N-glycosylated.required for stability and retention at the cell surface of pancreatic beta cells. |
| Function | Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells.may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate. |
| Peptide Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2Glucose Transporter Type 2 - LiverGlut-2 |
| Database Links | Reactome: R-MMU-189200Reactome: -MMU-422356Reactome: -MMU-8981373 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2 proteinGlucose Transporter Type 2 - Liver proteinGlut-2 proteinSlc2a2 proteinGlut2 protein |
Information sourced from Uniprot.org
