Glucose Transporter 8 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Applications
WB
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Dilution Range
WB: 1:500
Formulation
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction
Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.
Function
Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate.
Peptide Name
Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8Glucose Transporter Type 8Glut-8Glucose Transporter Type X1
Cell MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembranePrincipally IntracellularMay Move Between Intracellular Vesicles And The Plasma MembraneThe Dileucine Internalization Motif Is Critical For Intracellular Sequestration
Alternative Peptide Names
Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8 proteinGlucose Transporter Type 8 proteinGlut-8 proteinGlucose Transporter Type X1 proteinSLC2A8 proteinGLUT8 proteinGLUTX1 protein
