| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Dendrin/DDN Positive Control for STJ506042 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
DDN |
| Gene ID: |
23109 |
| Uniprot ID: |
DEND_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with Dendrin/DDN antibody STJ506042. |
| Immunogen: |
Purified Dendrin. |
| Tissue Specificity | Specifically expressed in brain and kidney. Expressed in kidney glomerular capillary loops (at protein level). |
| Function | Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein. |
| Peptide Name | Dendrin |
| Cellular Localisation | Cell ProjectionDendritic Spine MembranePeripheral Membrane ProteinCytoplasmEndoplasmic Reticulum MembraneCytoplasmic SidePerikaryonNucleusEnriched At The Cytoplasmic Insertion Of The Slit Diaphragm Into The Foot Process Of Podocytes And Associated With Polyribosomes In Dendrites |
| Alternative Peptide Names | Dendrin proteinDDN proteinKIAA0749 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
