Cynomolgus PVRIG protein (Recombinant) (C-hFc) (STJP020248)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Cynomolgus PVRIG Protein is expressed from Expi293 with hFc tag at the C-terminal.οΌIt contains Thr41-Asp171.
General Information
| Short Description | Recombinant-Cynomolgus PVRIG-C-hFc protein was developed in hek293 cells using the region Thr41-Asp171. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Recombinant Cynomolgus PVRIG Protein is expressed from Expi293 with hFc tag at the C-terminal.οΌIt contains Thr41-Asp171. |
| Immunogen Region | Thr41-Asp171 |
| Immunogen Sequence | TPEVWVQVQMEATELSSFTV HCGFLGPGSISLVTVSWGGP DGAGGTKLAVLHPELGTRQW APARQARWETQSSISLALED SGASSPFANTTFCCKFASFP EGSWESCGSLPPSSDPGLSA PPTPVPILRAD |
Additional Info
| Background | PVRIG (poliovirus receptor related immunoglobulin domain-containing protein) , also known as CD112 receptor (CD112R) , is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding. |
Information sourced from Uniprot.org