| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Immunogen Region: | Thr41-Asp171 |
| Immunogen: | Recombinant Cynomolgus PVRIG Protein is expressed from Expi293 with hFc tag at the C-terminal.；It contains Thr41-Asp171. |
| Immunogen Sequence: | TPEVWVQVQMEATELSSFTV HCGFLGPGSISLVTVSWGGP DGAGGTKLAVLHPELGTRQW APARQARWETQSSISLALED SGASSPFANTTFCCKFASFP EGSWESCGSLPPSSDPGLSA PPTPVPILRAD |
| Background | PVRIG (poliovirus receptor related immunoglobulin domain-containing protein) , also known as CD112 receptor (CD112R) , is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding. |
Information sourced from Uniprot.org