| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Cornichon Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Tissue Specificity | Highly expressed in heart, liver, skeletal muscle, pancreas, adrenal medulla and cortex, thyroid, testis, spleen, appendix, peripheral blood lymphocytes and bone marrow. Lower expression found in brain, placenta, lung, kidney, ovary, small intestine, stomach, lymph node, thymus and fetal liver. Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study). |
| Function | Involved in the selective transport and maturation of TGF-alpha family proteins. |
| Peptide Name | Protein Cornichon Homolog 1Cnih-1Cornichon Family Ampa Receptor Auxiliary Protein 1Protein Cornichon HomologT-Cell Growth-Associated Molecule 77Tgam77 |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-5694530 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneLocated Primarily In The ErMay Cycle Between The Er And The Golgi Apparatus |
| Alternative Peptide Names | Protein Cornichon Homolog 1 proteinCnih-1 proteinCornichon Family Ampa Receptor Auxiliary Protein 1 proteinProtein Cornichon Homolog proteinT-Cell Growth-Associated Molecule 77 proteinTgam77 proteinCNIH1 proteinCNIH proteinCNIL proteinUNQ155 proteinPRO181 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
