Cornichon Blocking Peptide is synthetically produced from the 90-120 sequence and is suitable for use in western blot applications.
Applications
Immunodepletion/Immunocompetition
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Formulation
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction
Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Synthetic peptide taken within amino acid region 90-120 on human Cornichon protein.
Immunogen Region
90-120
Additional Info
Tissue Specificity
Highly expressed in heart, liver, skeletal muscle, pancreas, adrenal medulla and cortex, thyroid, testis, spleen, appendix, peripheral blood lymphocytes and bone marrow. Lower expression found in brain, placenta, lung, kidney, ovary, small intestine, stomach, lymph node, thymus and fetal liver. Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study).
Function
Involved in the selective transport and maturation of TGF-alpha family proteins.
Peptide Name
Protein Cornichon Homolog 1Cnih-1Cornichon Family Ampa Receptor Auxiliary Protein 1Protein Cornichon HomologT-Cell Growth-Associated Molecule 77Tgam77
Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneLocated Primarily In The ErMay Cycle Between The Er And The Golgi Apparatus
Alternative Peptide Names
Protein Cornichon Homolog 1 proteinCnih-1 proteinCornichon Family Ampa Receptor Auxiliary Protein 1 proteinProtein Cornichon Homolog proteinT-Cell Growth-Associated Molecule 77 proteinTgam77 proteinCNIH1 proteinCNIH proteinCNIL proteinUNQ155 proteinPRO181 protein
