CD39 Blocking Peptide peptide (STJ505689)

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STJ505689-250
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Short Description :CD39 Blocking Peptide is synthetically produced from the 440-490 sequence and is suitable for use in western blot applications.
Applications:Immunodepletion/Immunocompetition
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation:Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol:ENTPD1
Gene ID:953
Uniprot ID:ENTP1_HUMAN
Immunogen:Synthetic peptide taken within amino acid region 440-490 on human EctoNucleoside TriPhosphate Diphosphohydrolase 1.
Immunogen Region:440-490
Tissue Specificity Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Highly expressed in placenta, lung, skeletal muscle, kidney.
Post Translational Modifications N-glycosylated. The N-terminus is blocked. Palmitoylated on Cys-13.which is required for caveola targeting.
Function Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.
Peptide Name Ectonucleoside Triphosphate Diphosphohydrolase 1
Atp Diphosphohydrolase
Atp-Dph
Atpdase
Ecto-Atp Diphosphohydrolase 1
Ecto-Atpdase 1
Ecto-Atpase 1
Ecto-Apyrase
Lymphoid Cell Activation Antigen
Nucleoside Triphosphate Diphosphohydrolase 1
Ntpdase1
Cd Antigen Cd39
Database Links Reactome: R-HSA-8850843
Reactome: R-HSA-9660826
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Caveola
Alternative Peptide Names Ectonucleoside Triphosphate Diphosphohydrolase 1 protein
Atp Diphosphohydrolase protein
Atp-Dph protein
Atpdase protein
Ecto-Atp Diphosphohydrolase 1 protein
Ecto-Atpdase 1 protein
Ecto-Atpase 1 protein
Ecto-Apyrase protein
Lymphoid Cell Activation Antigen protein
Nucleoside Triphosphate Diphosphohydrolase 1 protein
Ntpdase1 protein
Cd Antigen Cd39 protein
ENTPD1 protein
CD39 protein

Information sourced from Uniprot.org

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