CD39 Blocking Peptide peptide (STJ505689)

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STJ505689-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : CD39 Blocking Peptide is synthetically produced from the 440-490 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ENTPD1
Gene ID: 953
Uniprot ID: ENTP1_HUMAN
Immunogen Region: 440-490
Immunogen: Synthetic peptide taken within amino acid region 440-490 on human EctoNucleoside TriPhosphate Diphosphohydrolase 1.
Tissue Specificity Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Highly expressed in placenta, lung, skeletal muscle, kidney.
Post Translational Modifications N-glycosylated. The N-terminus is blocked. Palmitoylated on Cys-13.which is required for caveola targeting.
Function Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.
Peptide Name Ectonucleoside Triphosphate Diphosphohydrolase 1
Atp Diphosphohydrolase
Atp-Dph
Atpdase
Ecto-Atp Diphosphohydrolase 1
Ecto-Atpdase 1
Ecto-Atpase 1
Ecto-Apyrase
Lymphoid Cell Activation Antigen
Nucleoside Triphosphate Diphosphohydrolase 1
Ntpdase1
Cd Antigen Cd39
Database Links Reactome: R-HSA-8850843
Reactome: R-HSA-9660826
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Caveola
Alternative Peptide Names Ectonucleoside Triphosphate Diphosphohydrolase 1 protein
Atp Diphosphohydrolase protein
Atp-Dph protein
Atpdase protein
Ecto-Atp Diphosphohydrolase 1 protein
Ecto-Atpdase 1 protein
Ecto-Atpase 1 protein
Ecto-Apyrase protein
Lymphoid Cell Activation Antigen protein
Nucleoside Triphosphate Diphosphohydrolase 1 protein
Ntpdase1 protein
Cd Antigen Cd39 protein
ENTPD1 protein
CD39 protein

Information sourced from Uniprot.org

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