| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Bestrophin Blocking Peptide is synthetically produced from the 500-585 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
BEST1 |
| Gene ID: |
7439 |
| Uniprot ID: |
BEST1_HUMAN |
| Immunogen Region: |
500-585 |
| Immunogen: |
Synthetic peptide taken within amino acid region 500-585 on human Bestrophin-1 isoform 1 protein. |
| Tissue Specificity | Predominantly expressed in the basolateral membrane of the retinal pigment epithelium. |
| Post Translational Modifications | Phosphorylated by PP2A. |
| Function | Forms calcium-sensitive chloride channels. Highly permeable to bicarbonate. |
| Peptide Name | Bestrophin-1Tu15bVitelliform Macular Dystrophy Protein 2 |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
| Alternative Peptide Names | Bestrophin-1 proteinTu15b proteinVitelliform Macular Dystrophy Protein 2 proteinBEST1 proteinVMD2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
