ASIC2 Blocking Peptide for STJ500176 peptide (STJ505573)

SKU:
STJ505573-250

£289.50
Shipping:
Free Shipping
Current Stock:
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: ASIC2 Blocking Peptide for STJ500176 is synthetically produced from the 450-512 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ASIC2
Gene ID: 40
Uniprot ID: ASIC2_HUMAN
Immunogen Region: 450-512
Specificity: This blocking peptide is recommended for use in combination with ASIC2 antibody, STJ500176
Immunogen: Synthetic peptide taken within amino acid region 450-512 on human Acid-sensing ion channel 2 protein.
Tissue Specificity Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary.
Function Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
Peptide Name Acid-Sensing Ion Channel 2
Asic2
Amiloride-Sensitive Brain Sodium Channel
Amiloride-Sensitive Cation Channel 1 - Neuronal
Amiloride-Sensitive Cation Channel Neuronal 1
Brain Sodium Channel 1
Bnc1
Bnac1
Mammalian Degenerin Homolog
Mdeg
Database Links Reactome: R-HSA-2672351
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Localized At The Plasma Membrane Of Neurons
In The Soma And Punctated Peripheral Processes
Alternative Peptide Names Acid-Sensing Ion Channel 2 protein
Asic2 protein
Amiloride-Sensitive Brain Sodium Channel protein
Amiloride-Sensitive Cation Channel 1 - Neuronal protein
Amiloride-Sensitive Cation Channel Neuronal 1 protein
Brain Sodium Channel 1 protein
Bnc1 protein
Bnac1 protein
Mammalian Degenerin Homolog protein
Mdeg protein
ASIC2 protein
ACCN protein
ACCN1 protein
BNAC1 protein
MDEG protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance