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ASIC2 Blocking Peptide for STJ500176 peptide (STJ505573)

ASIC2 Blocking Peptide for STJ500176 peptide (STJ505573)

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STJ505573-250

£289.50

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Product Properties
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Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	ASIC2 Blocking Peptide for STJ500176 is synthetically produced from the 450-512 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	ASIC2
Gene ID:	40
Uniprot ID:	ASIC2_HUMAN
Immunogen Region:	450-512
Specificity:	This blocking peptide is recommended for use in combination with ASIC2 antibody, STJ500176
Immunogen:	Synthetic peptide taken within amino acid region 450-512 on human Acid-sensing ion channel 2 protein.

Tissue Specificity	Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary.
Function	Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
Peptide Name	Acid-Sensing Ion Channel 2 Asic2 Amiloride-Sensitive Brain Sodium Channel Amiloride-Sensitive Cation Channel 1 - Neuronal Amiloride-Sensitive Cation Channel Neuronal 1 Brain Sodium Channel 1 Bnc1 Bnac1 Mammalian Degenerin Homolog Mdeg
Database Links	Reactome: R-HSA-2672351
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Localized At The Plasma Membrane Of Neurons In The Soma And Punctated Peripheral Processes
Alternative Peptide Names	Acid-Sensing Ion Channel 2 protein Asic2 protein Amiloride-Sensitive Brain Sodium Channel protein Amiloride-Sensitive Cation Channel 1 - Neuronal protein Amiloride-Sensitive Cation Channel Neuronal 1 protein Brain Sodium Channel 1 protein Bnc1 protein Bnac1 protein Mammalian Degenerin Homolog protein Mdeg protein ASIC2 protein ACCN protein ACCN1 protein BNAC1 protein MDEG protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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