| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Zyxin (250-350) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S8MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZYX |
| Gene ID: |
7791 |
| Uniprot ID: |
ZYX_HUMAN |
| Immunogen Region: |
250-350 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Zyxin (Q15942). |
| Immunogen Sequence: |
TQPRGPPASSPAPAPKFSPV TPKFTPVASKFSPGAPGGSG SQPNQKLGHPEALSAGTGSP QPPSFTYAQQREKPRVQEKQ HPVPPPAQNQNQVRSPGAPG P |
| Function | Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression. |
| Protein Name | ZyxinZyxin-2 |
| Cellular Localisation | CytoplasmCytoskeletonNucleusCell JunctionFocal AdhesionAssociates With The Actin Cytoskeleton Near The Adhesion PlaquesEnters The Nucleus In The Presence Of Hesx1 |
| Alternative Antibody Names | Anti-Zyxin antibodyAnti-Zyxin-2 antibodyAnti-ZYX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
