Anti-ZP4 antibody (231-280 aa) (STJ96361)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ZP4 at the amino acid range 231-280
General Information
| Short Description | Rabbit polyclonal anti-Zona pellucida sperm-binding protein 4 (231-280 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZP4 |
| Gene ID | 57829 |
| Uniprot ID | ZP4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ZP4 at the amino acid range 231-280 |
| Immunogen Region | 231-280 aa |
| Specificity | ZP4 Polyclonal Antibody detects endogenous levels of ZP4 protein. |
Additional Info
| Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. |
| Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor. |
| Protein Name | Zona Pellucida Sperm-Binding Protein 4Zona Pellucida Glycoprotein 4Zp-4Zona Pellucida Protein B Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 4 |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 4: Zona PellucidaCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Zona Pellucida Sperm-Binding Protein 4 antibodyAnti-Zona Pellucida Glycoprotein 4 antibodyAnti-Zp-4 antibodyAnti-Zona Pellucida Protein B Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 4 antibodyAnti-ZP4 antibodyAnti-ZPB antibody |
Information sourced from Uniprot.org