Anti-ZNF9/CNBP antibody (C-Term) (STJ70911)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-ZNF9/CNBP (C-Term) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications. |
| Applications | Pep-ELISA/WB/IF/FC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 20kDa band observed in Human Skeletal Muscle lysates and in lysates of cell lines Daudi, MCF7, MOLT-4 and Neuro-2a (calculated MW of 19.5kDa according to Human NP_003409.1 and Mo |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CNBP |
| Gene ID | 7555 |
| Uniprot ID | CNBP_HUMAN |
| Accession Number | NP_003409.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | GESGHLARECTIE |
Additional Info
| Post Translational Modifications | Arginine methylation by PRMT1 in the Arg/Gly-rich region impedes RNA binding. |
| Function | Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression. Has a role as transactivator of the Myc promoter. Binds single-stranded RNA in a sequence-specific manner. Isoform 1: Binds G-rich elements in target mRNA coding sequences. Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs. Isoform 2: Binds to RNA. Isoform 4: Binds to RNA. Isoform 5: Binds to RNA. Isoform 6: Binds to RNA. Isoform 8: Binds to RNA. |
| Protein Name | Cchc-Type Zinc Finger Nucleic Acid Binding ProteinCellular Nucleic Acid-Binding ProteinCnbpZinc Finger Protein 9 |
| Database Links | Reactome: R-HSA-9705671 |
| Cellular Localisation | NucleusCytoplasmEndoplasmic ReticulumIsoform 1: CytoplasmIsoform 2: CytoplasmIsoform 4: CytoplasmIsoform 5: CytoplasmIsoform 6: CytoplasmIsoform 8: Cytoplasm |
| Alternative Antibody Names | Anti-Cchc-Type Zinc Finger Nucleic Acid Binding Protein antibodyAnti-Cellular Nucleic Acid-Binding Protein antibodyAnti-Cnbp antibodyAnti-Zinc Finger Protein 9 antibodyAnti-CNBP antibodyAnti-RNF163 antibodyAnti-ZNF9 antibody |
Information sourced from Uniprot.org