| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Zinc finger FYVE domain-containing protein 9 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZFYVE9 |
| Gene ID: | 9372 |
| Uniprot ID: | ZFYV9_HUMAN |
| Specificity: | This antibody detects endogenous levels of SARA at Human |
| Immunogen: | Synthesized peptide derived from human SARA |
| Function | Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. |
| Protein Name | Zinc Finger Fyve Domain-Containing Protein 9Mothers Against Decapentaplegic Homolog-Interacting ProteinMadh-Interacting ProteinNovel Serine ProteaseNspReceptor Activation AnchorHsaraSmad Anchor For Receptor Activation |
| Database Links | Reactome: R-HSA-2173788 O95405-1Reactome: R-HSA-2173789 O95405-1Reactome: R-HSA-3304356 O95405-1Reactome: R-HSA-3656532 O95405-1 |
| Cellular Localisation | CytoplasmEarly Endosome Membrane |
| Alternative Antibody Names | Anti-Zinc Finger Fyve Domain-Containing Protein 9 antibodyAnti-Mothers Against Decapentaplegic Homolog-Interacting Protein antibodyAnti-Madh-Interacting Protein antibodyAnti-Novel Serine Protease antibodyAnti-Nsp antibodyAnti-Receptor Activation Anchor antibodyAnti-Hsara antibodyAnti-Smad Anchor For Receptor Activation antibodyAnti-ZFYVE9 antibodyAnti-MADHIP antibodyAnti-SARA antibodyAnti-SMADIP antibody |
Information sourced from Uniprot.org
