| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Probable ribonuclease ZC3H12D (87-137) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZC3H12D |
| Gene ID: |
340152 |
| Uniprot ID: |
ZC12D_HUMAN |
| Immunogen Region: |
87-137 |
| Specificity: |
This antibody detects endogenous levels of human ZC12D |
| Immunogen: |
Synthesized peptide derived from human ZC12D AA range: 87-137 |
| Function | May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages. Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation. |
| Protein Name | Probable Ribonuclease Zc3h12dMcp-Induced Protein 4Transformed Follicular LymphomaZinc Finger Ccch Domain-Containing Protein 12dP34 |
| Cellular Localisation | CytoplasmP-BodyColocalizes With Zc3h12a In Gw Bodies (Gwbs)Isoform 1: CytoplasmLocalized As Discrete GranulesColocalized With Mrna-Processing Body MarkersAgo2 And Dcp1aBut Not With A Stress Granule MakerTia1In The CytoplasmIsoform 3: CytoplasmNucleus |
| Alternative Antibody Names | Anti-Probable Ribonuclease Zc3h12d antibodyAnti-Mcp-Induced Protein 4 antibodyAnti-Transformed Follicular Lymphoma antibodyAnti-Zinc Finger Ccch Domain-Containing Protein 12d antibodyAnti-P34 antibodyAnti-ZC3H12D antibodyAnti-C6orf95 antibodyAnti-MCPIP4 antibodyAnti-TFL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
