Anti-YRDC antibody (STJA0004553)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human YRDC
General Information
| Short Description | Rabbit polyclonal antibody anti-Threonylcarbamoyl-Amp Synthase is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications. |
| Applications | WB/IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | WB 1:500-1:2000, IHC 1:25-1:100 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | YRDC |
| Gene ID | 79693 |
| Uniprot ID | YRDC_HUMAN |
| Immunogen | Synthetic peptide of human YRDC |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters. |
| Protein Name | Threonylcarbamoyl-Amp SynthaseDopamine Receptor-Interacting Protein 3Ischemia/Reperfusion-Inducible Protein HomologHirip |
| Cellular Localisation | CytoplasmMitochondrionCell MembranePeripheral Membrane ProteinA Large Fraction Localizes In The CytoplasmWhereas A Smaller Fraction Is Imported To Mitochondria |
| Alternative Antibody Names | Anti-Threonylcarbamoyl-Amp Synthase antibodyAnti-Dopamine Receptor-Interacting Protein 3 antibodyAnti-Ischemia/Reperfusion-Inducible Protein Homolog antibodyAnti-Hirip antibodyAnti-YRDC antibodyAnti-DRIP3 antibodyAnti-IRIP antibody |
Information sourced from Uniprot.org