Anti-XIRP1 antibody (1-51 aa) (STJ195123)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human XIRP1 at the amino acid range 1-51
General Information
| Short Description | Rabbit polyclonal anti-Xin actin-binding repeat-containing protein 1 (1-51 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | XIRP1 |
| Gene ID | 165904 |
| Uniprot ID | XIRP1_HUMAN |
| Immunogen | Synthesized peptide derived from the human XIRP1 at the amino acid range 1-51 |
| Immunogen Region | 1-51 aa |
| Specificity | This antibody detects endogenous levels of XIRP1 at Human/Mouse |
Additional Info
| Function | Protects actin filaments from depolymerization. Required for correct cardiac intercalated disk ultrastructure via maintenance of cell-cell adhesion stability, and as a result maintains cardiac organ morphology, conductance and heart beat rhythm. Required for development of normal skeletal muscle morphology and muscle fiber type composition. Plays a role in regulating muscle satellite cell activation and survival, as a result promotes muscle fiber recovery from injury and fatigue. |
| Protein Name | Xin Actin-Binding Repeat-Containing Protein 1Cardiomyopathy-Associated Protein 1 |
| Database Links | |
| Cellular Localisation | Cell JunctionAdherens JunctionDesmosomeColocalizes With Actin Stress Fibers |
| Alternative Antibody Names | Anti-Xin Actin-Binding Repeat-Containing Protein 1 antibodyAnti-Cardiomyopathy-Associated Protein 1 antibodyAnti-XIRP1 antibodyAnti-CMYA1 antibodyAnti-XIN antibody |
Information sourced from Uniprot.org