Anti-WNT5B antibody (181-342) (STJ110611)

Name: Anti-WNT5B antibody (181-342) (STJ110611)
SKU: STJ110611
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ110611

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Short Description	Rabbit polyclonal WNT5B (181-342) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:50-1:100 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	WNT5B
Gene ID	81029
Uniprot ID	WNT5B_HUMAN
Immunogen Region	181-342
Immunogen Sequence	ASVFGRVMQIGSRETAFTHA VSAAGVVNAISRACREGELS TCGCSRTARPKDLPRDWLWG GCGDNVEYGYRFAKEFVDAR EREKNFAKGSEEQGRVLMNL QNNEAGRRAVYKMADVACKC HGVSGSCSLKTCWLQLAEFR KVGDRLKEKYDSAAAMRVTR KGRLELVNSRFTQPTPEDLV YVDPSPDYCLRNESTGSLGT
Specificity	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human WNT5B (NP_110402.2).

Post Translational Modifications	Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function	Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Protein Name	Protein Wnt-5b
Database Links	Reactome: R-HSA-3238698 Reactome: R-HSA-4086400
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Protein Wnt-5b antibody Anti-WNT5B antibody

Information sourced from Uniprot.org