Anti-WNT2B antibody (200-300) [S7MR] (STJ11103037)

Name: Anti-WNT2B antibody (200-300) [S7MR] (STJ11103037)
SKU: STJ11103037
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11103037

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Short Description	Rabbit monoclonal WNT2B (200-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S7MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:1000-1:6000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	WNT2B
Gene ID	7482
Uniprot ID	WNT2B_HUMAN
Immunogen Region	200-300
Immunogen Sequence	KAFVDAKEKRLKDARALMNL HNNRCGRTAVRRFLKLECKC HGVSGSCTLRTCWRALSDFR RTGDYLRRRYDGAVQVMATQ DGANFTAARQGYRRATRTDL V
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human WNT2B (Q93097).

Tissue Specificity	Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.
Post Translational Modifications	Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function	Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.
Protein Name	Protein Wnt-2b Protein Wnt-13
Database Links	Reactome: R-HSA-3238698 Reactome: R-HSA-373080
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Protein Wnt-2b antibody Anti-Protein Wnt-13 antibody Anti-WNT2B antibody Anti-WNT13 antibody

Information sourced from Uniprot.org