Anti-WBP11 antibody (540-641) (STJ118631)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal WBP11 (540-641) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | WBP11 |
| Gene ID | 51729 |
| Uniprot ID | WBP11_HUMAN |
| Immunogen Region | 540-641 |
| Immunogen Sequence | LIQRPKADDTSAATIEKKAT ATISAKPQITNPKAEITRFV PTALRVRRENKGATAAPQRK SEDDSAVPLAKAAPKSGPSV PVSVQTKDDVYEAFMKEMEG LL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 540-641 of human WBP11 (NP_057396.1). |
Additional Info
| Tissue Specificity | Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung. |
| Function | Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity. |
| Protein Name | Ww Domain-Binding Protein 11Wbp-11Npw38-Binding ProteinNpwbpSh3 Domain-Binding Protein Snp70Splicing Factor That Interacts With Pqbp-1 And Pp1 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusCytoplasmPredominantly Located In The Nucleus With Granular Heterogeneous DistributionExcluded From Nucleoli In Interphase CellsDistributed Throughout Cytoplasm In Dividing CellsColocalized With Sc35 And U2b In The NucleusIn The CytoplasmAssociates With The Intermediate Filament Protein Vimentin |
| Alternative Antibody Names | Anti-Ww Domain-Binding Protein 11 antibodyAnti-Wbp-11 antibodyAnti-Npw38-Binding Protein antibodyAnti-Npwbp antibodyAnti-Sh3 Domain-Binding Protein Snp70 antibodyAnti-Splicing Factor That Interacts With Pqbp-1 And Pp1 antibodyAnti-WBP11 antibodyAnti-NPWBP antibodyAnti-SIPP1 antibodyAnti-SNP70 antibody |
Information sourced from Uniprot.org