| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse/Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-VTI1A (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Vti1a |
| Gene ID: | 53611 |
| Uniprot ID: | VTI1A_MOUSE |
| Immunogen Region: | C-Term |
| Specificity: | Specific for VTI1A. |
| Immunogen: | A synthetic peptide from the c-terminal region of mouse VTI1A (Vesicle transport v-SNARE protein Vti1-like 2) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be concerned with increased secretion of cytokines associated with cellular senescence. |
| Protein Name | Vesicle Transport Through Interaction With T-Snares Homolog 1aVesicle Transport V-Snare Protein Vti1-Like 2Vti1-Rp2 |
| Database Links | Reactome: R-MMU-6811438Reactome: -MMU-6811440 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Iv Membrane Protein |
| Alternative Antibody Names | Anti-Vesicle Transport Through Interaction With T-Snares Homolog 1a antibodyAnti-Vesicle Transport V-Snare Protein Vti1-Like 2 antibodyAnti-Vti1-Rp2 antibodyAnti-Vti1a antibodyAnti-Vti1 antibodyAnti-Vti1l2 antibody |
Information sourced from Uniprot.org