| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-VPS37B (60-170) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
VPS37B |
| Gene ID: |
79720 |
| Uniprot ID: |
VP37B_HUMAN |
| Immunogen Region: |
60-170 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 60-170 of human VPS37B (NP_078943.1). |
| Immunogen Sequence: |
LLYQPQLDTLKARLTQKYQE LQVLFEAYQIKKTKLDRQSS SASLETLLALLQAEGAKIEE DTENMAEKFLDGELPLDSFI DVYQSKRKLAHMRRVKIEKL QEMVLKGQRLP |
| Tissue Specificity | Widely expressed. Expressed in macrophages and lymphocytes. |
| Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. |
| Protein Name | Vacuolar Protein Sorting-Associated Protein 37bHvps37bEscrt-I Complex Subunit Vps37b |
| Database Links | Reactome: R-HSA-162588Reactome: R-HSA-174490Reactome: R-HSA-917729Reactome: R-HSA-9610379Reactome: R-HSA-9615710 |
| Cellular Localisation | Late Endosome MembranePeripheral Membrane ProteinRecruited To The Endosomal Membrane In A Vps4a-Dependent Fashion |
| Alternative Antibody Names | Anti-Vacuolar Protein Sorting-Associated Protein 37b antibodyAnti-Hvps37b antibodyAnti-Escrt-I Complex Subunit Vps37b antibodyAnti-VPS37B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
