Anti-USP54 antibody (STJ190910)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Inactive ubiquitin carboxyl-terminal hydrolase 54 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USP54 |
| Gene ID | 159195 |
| Uniprot ID | UBP54_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | UBP54 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Deubiquitinase that specifically mediates 'Lys-63'-linked deubiquitination of substrates with a polyubiquitin chain composed of at least 3 ubiquitins. Specifically recognizes ubiquitin chain in position S2 and catalyzes cleavage of polyubiquitin within 'Lys-63'-linked chains. Not able to deubiquitinate substrates with shorter ubiquitin chains. Mediates deubiquitination of PLK4, maintaining PLK4 stability by reducing its ubiquitination-mediated degradation. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 54Ubiquitin-Specific Peptidase 54 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 54 antibodyAnti-Ubiquitin-Specific Peptidase 54 antibodyAnti-USP54 antibodyAnti-C10orf29 antibody |
Information sourced from Uniprot.org