| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Uroporphyrinogen-III synthase (25-75 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UROS |
| Gene ID: |
7390 |
| Uniprot ID: |
HEM4_HUMAN |
| Immunogen Region: |
25-75 aa |
| Specificity: |
This antibody detects endogenous levels of HEM4 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human HEM4 at the amino acid range 25-75 |
| Function | Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme). |
| Protein Name | Uroporphyrinogen-Iii SynthaseUroiiisUrosHydroxymethylbilane Hydrolyase CyclizingUroporphyrinogen-Iii Cosynthase |
| Database Links | Reactome: R-HSA-189451 |
| Alternative Antibody Names | Anti-Uroporphyrinogen-Iii Synthase antibodyAnti-Uroiiis antibodyAnti-Uros antibodyAnti-Hydroxymethylbilane Hydrolyase Cyclizing antibodyAnti-Uroporphyrinogen-Iii Cosynthase antibodyAnti-UROS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
