| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Netrin receptor UNC5D (160-240 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UNC5D |
| Gene ID: | 137970 |
| Uniprot ID: | UNC5D_HUMAN |
| Immunogen Region: | 160-240 aa |
| Specificity: | UNC5D Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 160-240 |
| Function | Receptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell. |
| Protein Name | Netrin Receptor Unc5dProtein Unc-5 Homolog 4Protein Unc-5 Homolog D |
| Database Links | Reactome: R-HSA-418886 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Netrin Receptor Unc5d antibodyAnti-Protein Unc-5 Homolog 4 antibodyAnti-Protein Unc-5 Homolog D antibodyAnti-UNC5D antibodyAnti-KIAA1777 antibodyAnti-UNC5H4 antibodyAnti-UNQ6012 antibodyAnti-PRO34692 antibody |
Information sourced from Uniprot.org