Anti-UBTF antibody (501-550 aa) (STJ96169)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human UBF1 at the amino acid range 501-550
General Information
| Short Description | Rabbit polyclonal anti-Nucleolar transcription factor 1 (501-550 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBTF |
| Gene ID | 7343 |
| Uniprot ID | UBF1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human UBF1 at the amino acid range 501-550 |
| Immunogen Region | 501-550 aa |
| Specificity | UBF-1 Polyclonal Antibody detects endogenous levels of UBF-1 protein. |
Additional Info
| Function | Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I (Pol I) through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element and can activate Pol I promoter escape. |
| Protein Name | Nucleolar Transcription Factor 1Autoantigen Nor-90Upstream-Binding Factor 1Ubf-1 |
| Database Links | Reactome: R-HSA-427413Reactome: R-HSA-73728Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Nucleolar Transcription Factor 1 antibodyAnti-Autoantigen Nor-90 antibodyAnti-Upstream-Binding Factor 1 antibodyAnti-Ubf-1 antibodyAnti-UBTF antibodyAnti-UBF antibodyAnti-UBF1 antibody |
Information sourced from Uniprot.org