| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBP1 |
| Gene ID: | 7342 |
| Uniprot ID: | UBIP1_HUMAN |
| Immunogen Region: | 280-380 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 280-380 of human UBP1 (NP_055332.3). |
| Immunogen Sequence: | IEDAVEHEQKKSSKRTLPAD YGDSLAKRGSCSPWPDAPTA YVNNSPSPAPTFTSPQQSTC SVPDSNSSSPNHQGDGASQT SGEQIQPSATIQETQQWLLK N |
| Tissue Specificity | Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines. |
| Function | Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. |
| Protein Name | Upstream-Binding Protein 1Transcription Factor Lbp-1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Upstream-Binding Protein 1 antibodyAnti-Transcription Factor Lbp-1 antibodyAnti-UBP1 antibodyAnti-LBP1 antibody |
Information sourced from Uniprot.org