| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UBP1 (280-380) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UBP1 |
| Gene ID: |
7342 |
| Uniprot ID: |
UBIP1_HUMAN |
| Immunogen Region: |
280-380 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 280-380 of human UBP1 (NP_055332.3). |
| Immunogen Sequence: |
IEDAVEHEQKKSSKRTLPAD YGDSLAKRGSCSPWPDAPTA YVNNSPSPAPTFTSPQQSTC SVPDSNSSSPNHQGDGASQT SGEQIQPSATIQETQQWLLK N |
| Tissue Specificity | Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines. |
| Function | Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. |
| Protein Name | Upstream-Binding Protein 1Transcription Factor Lbp-1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Upstream-Binding Protein 1 antibodyAnti-Transcription Factor Lbp-1 antibodyAnti-UBP1 antibodyAnti-LBP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
