Anti-UBAP2L antibody (561-610) (STJ94490)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human UBAP2L. AA range:561-610
General Information
| Short Description | Rabbit polyclonal anti-Ubiquitin-associated protein 2-like (561-610) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBAP2L |
| Gene ID | 9898 |
| Uniprot ID | UBP2L_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human UBAP2L. AA range:561-610 |
| Immunogen Region | 561-610 |
| Specificity | NICE4 Polyclonal Antibody detects endogenous levels of NICE4 protein. |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Acetylated. |
| Function | Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage. Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs). Is a regulator of stress granule assembly, required for their efficient formation. Required for proper brain development and neocortex lamination. |
| Protein Name | Ubiquitin-Associated Protein 2-LikeProtein Nice-4Rna Polymerase Ii Degradation Factor Ubap2l |
| Database Links | |
| Cellular Localisation | NucleusChromosomeCytoplasmStress GranuleAssociates With Nuclear Chromatin |
| Alternative Antibody Names | Anti-Ubiquitin-Associated Protein 2-Like antibodyAnti-Protein Nice-4 antibodyAnti-Rna Polymerase Ii Degradation Factor Ubap2l antibodyAnti-UBAP2L antibodyAnti-KIAA0144 antibodyAnti-NICE4 antibody |
Information sourced from Uniprot.org