| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ubiquitin-associated protein 2-like (561-610) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBAP2L |
| Gene ID: | 9898 |
| Uniprot ID: | UBP2L_HUMAN |
| Immunogen Region: | 561-610 |
| Specificity: | NICE4 Polyclonal Antibody detects endogenous levels of NICE4 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human UBAP2L. AA range:561-610 |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Acetylated. |
| Function | Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage. Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs). Is a regulator of stress granule assembly, required for their efficient formation. Required for proper brain development and neocortex lamination. |
| Protein Name | Ubiquitin-Associated Protein 2-LikeProtein Nice-4Rna Polymerase Ii Degradation Factor Ubap2l |
| Database Links | |
| Cellular Localisation | NucleusChromosomeCytoplasmStress GranuleAssociates With Nuclear Chromatin |
| Alternative Antibody Names | Anti-Ubiquitin-Associated Protein 2-Like antibodyAnti-Protein Nice-4 antibodyAnti-Rna Polymerase Ii Degradation Factor Ubap2l antibodyAnti-UBAP2L antibodyAnti-KIAA0144 antibodyAnti-NICE4 antibody |
Information sourced from Uniprot.org
