| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ubiquitin-like modifier-activating enzyme 6 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UBA6 |
| Gene ID: |
55236 |
| Uniprot ID: |
UBA6_HUMAN |
| Specificity: |
UBA6 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility. |
| Protein Name | Ubiquitin-Like Modifier-Activating Enzyme 6Ubiquitin-Activating Enzyme 6Monocyte Protein 4Mop-4Ubiquitin-Activating Enzyme E1-Like Protein 2E1-L2 |
| Database Links | Reactome: R-HSA-8866652Reactome: R-HSA-983168 |
| Alternative Antibody Names | Anti-Ubiquitin-Like Modifier-Activating Enzyme 6 antibodyAnti-Ubiquitin-Activating Enzyme 6 antibodyAnti-Monocyte Protein 4 antibodyAnti-Mop-4 antibodyAnti-Ubiquitin-Activating Enzyme E1-Like Protein 2 antibodyAnti-E1-L2 antibodyAnti-UBA6 antibodyAnti-MOP4 antibodyAnti-UBE1L2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
