• Western blot analysis of extracts of various cell lines, using Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) rabbit monoclonal antibody (STJ11102389) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
  • Western blot analysis of extracts of various cell lines, using Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) Rabbit monoclonal antibody (STJ11102389) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-TXNRD2 antibody (1-100) [S9MR] (STJ11102389)

SKU:
STJ11102389

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-TXNRD2 (1-100) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S9MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TXNRD2
Gene ID: 10587
Uniprot ID: TRXR2_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thioredoxin reductase 2 (TXNRD2 ) (NP_006431.2).
Immunogen Sequence: MAAMAVALRGLGGRFRWRTQ AVAGGVRGAARGAAAGQRDY DLLVVGGGSGGLACAKEAAQ LGRKVAVVDYVEPSPQGTRW GLGGTCVNVGCIPKKLMHQA
Tissue Specificity Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. high levels in kidney, whereas levels are low. High expression is observed in the adrenal cortex.
Function Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
Protein Name Thioredoxin Reductase 2 - Mitochondrial
Selenoprotein Z
Selz
Tr-Beta
Thioredoxin Reductase Tr3
Database Links Reactome: R-HSA-3299685
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Thioredoxin Reductase 2 - Mitochondrial antibody
Anti-Selenoprotein Z antibody
Anti-Selz antibody
Anti-Tr-Beta antibody
Anti-Thioredoxin Reductase Tr3 antibody
Anti-TXNRD2 antibody
Anti-KIAA1652 antibody
Anti-TRXR2 antibody

Information sourced from Uniprot.org

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