| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TXNL4A |
| Gene ID: | 10907 |
| Uniprot ID: | TXN4A_HUMAN |
| Immunogen Region: | 1-142 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human TXNL4A (NP_006692.1). |
| Immunogen Sequence: | MSYMLPHLHNGWQVDQAILS EEDRVVVIRFGHDWDPTCMK MDEVLYSIAEKVKNFAVIYL VDITEVPDFNKMYELYDPCT VMFFFRNKHIMIDLGTGNNN KINWAMEDKQEMVDIIETVY RGARKGRGLVVSPKDYSTKY RY |
| Post Translational Modifications | The disulfide bond seen in structures determined by X-ray crystallography and NMR is not essential for protein folding and function. |
| Function | Plays a role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). |
| Protein Name | Thioredoxin-Like Protein 4aDim1 Protein HomologSpliceosomal U5 Snrnp-Specific 15 Kda ProteinThioredoxin-Like U5 Snrnp Protein U5-15kd |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Thioredoxin-Like Protein 4a antibodyAnti-Dim1 Protein Homolog antibodyAnti-Spliceosomal U5 Snrnp-Specific 15 Kda Protein antibodyAnti-Thioredoxin-Like U5 Snrnp Protein U5-15kd antibodyAnti-TXNL4A antibodyAnti-DIM1 antibodyAnti-TXNL4 antibody |
Information sourced from Uniprot.org