Anti-TWF1 antibody (179-229 aa) (STJ195110)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TWF1 at the amino acid range 179-229
General Information
| Short Description | Rabbit polyclonal anti-Twinfilin-1 (179-229 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TWF1 |
| Gene ID | 5756 |
| Uniprot ID | TWF1_HUMAN |
| Immunogen | Synthesized peptide derived from the human TWF1 at the amino acid range 179-229 |
| Immunogen Region | 179-229 aa |
| Specificity | This antibody detects endogenous levels of TWF1 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | Phosphorylated on serine and threonine residues. |
| Function | Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. |
| Protein Name | Twinfilin-1Protein A6Protein Tyrosine Kinase 9 |
| Database Links | Reactome: R-HSA-9013418Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | CytoplasmCytoskeletonDiffuse Cytoplasmic Localization With Perinuclear And G-Actin-Rich Cortical Actin Structures SublocalizationAlso Found At Membrane Ruffles And Cell-Cell Contacts |
| Alternative Antibody Names | Anti-Twinfilin-1 antibodyAnti-Protein A6 antibodyAnti-Protein Tyrosine Kinase 9 antibodyAnti-TWF1 antibodyAnti-PTK9 antibody |
Information sourced from Uniprot.org