• Immunofluorescence analysis of NIH-3T3 cells using TWEAKR/Fn14/CD266 Rabbit monoclonal antibody (STJ11103597) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using TWEAKR/Fn14/CD266 Rabbit monoclonal antibody (STJ11103597) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-TWEAKR/Fn14/CD266 antibody (50-129) [S7MR] (STJ11103597)

SKU:
STJ11103597

£212.50 - £501.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-TWEAKR/Fn14/CD266 (50-129) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: S7MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFRSF12A
Gene ID: 51330
Uniprot ID: TNR12_HUMAN
Immunogen Region: 50-129
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-129 of human TWEAKR/Fn14/CD266 (Q9NP84).
Immunogen Sequence: MDCASCRARPHSDFCLGCAA APPAPFRLLWPILGGALSLT FVLGLLSGFLVWRRCRRREK FTTPIEETGGEGCPAVALIQ
Tissue Specificity Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Function Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 12a
Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14
Fgf-Inducible 14
Tweak-Receptor
Tweakr
Cd Antigen Cd266
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5676594
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 12a antibody
Anti-Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14 antibody
Anti-Fgf-Inducible 14 antibody
Anti-Tweak-Receptor antibody
Anti-Tweakr antibody
Anti-Cd Antigen Cd266 antibody
Anti-TNFRSF12A antibody
Anti-FN14 antibody

Information sourced from Uniprot.org

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