Anti-TTC7A antibody (1-300) (STJ11103395)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TTC7A (1-300) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TTC7A |
| Gene ID | 57217 |
| Uniprot ID | TTC7A_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MAAKGAHGSYLKVESELERC RAEGHWDRMPELVRQLQTLS MPGGGGNRRGSPSAAFTFPD TDDFGKLLLAEALLEQCLKE NHAKIKDSMPLLEKNEPKMS EAKNYLSSILNHGRLSPQYM CEAMLILGKLHYVEGSYRDA ISMYARAGIDDMSMENKPLY QMRLLSEAFVIKGLSLERLP NSIASRFRLTEREEEVITCF ERASWIAQVFLQELEKTTNN STSRHLKGCHPLDYELTYF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC7A (NP_001275880.1). |
Additional Info
| Tissue Specificity | Expressed in epithelial cells of the intestine, thymus, and pancreas (at protein level). |
| Function | Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, plays a central role in bridging PI4KA to EFR3B and HYCC1, via direct interactions. |
| Protein Name | Tetratricopeptide Repeat Protein 7aTpr Repeat Protein 7a |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneLocalizes To The Cytosol And Is Recruited To The Plasma Membrane Following Interaction With Efr3 (Efr3a Or Efr3b) |
| Alternative Antibody Names | Anti-Tetratricopeptide Repeat Protein 7a antibodyAnti-Tpr Repeat Protein 7a antibodyAnti-TTC7A antibodyAnti-KIAA1140 antibodyAnti-TTC7 antibody |
Information sourced from Uniprot.org