Anti-TSN antibody [4C6] (STJA0032725)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant human TSN protein fragments expressed in E.coli.
General Information
| Short Description | Mouse monoclonal anti-TSN for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 4C6 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TSN |
| Gene ID | 7247 |
| Uniprot ID | TSN_HUMAN |
| Immunogen | Purified recombinant human TSN protein fragments expressed in E.coli. |
Additional Info
| Function | DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots. Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand. |
| Protein Name | TranslinComponent 3 Of Promoter Of RiscC3po |
| Database Links | Reactome: R-HSA-426486 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Translin antibodyAnti-Component 3 Of Promoter Of Risc antibodyAnti-C3po antibodyAnti-TSN antibody |
Information sourced from Uniprot.org