| Host: |
Rabbit |
| Applications: |
WB/IHC-P/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRMT61A |
| Gene ID: |
115708 |
| Uniprot ID: |
TRM61_HUMAN |
| Immunogen Region: |
1-289 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human TRMT61A (NP_689520.2). |
| Immunogen Sequence: |
MSFVAYEELIKEGDTAILSL GHGAMVAVRVQRGAQTQTRH GVLRHSVDLIGRPFGSKVTC GRGGWVYVLHPTPELWTLNL PHRTQILYSTDIALITMMLE LRPGSVVCESGTGSGSVSHA IIRTIAPTGHLHTVEFHQQR AEKAREEFQEHRVGRWVTVR TQDVCRSGFGVSHVADAVFL DIPSPWEAVGHAWDALKVEG GRFCSFSPCIEQVQRTCQAL AARGFSELSTLEVLPQVYN |
| Function | Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries. |
| Protein Name | TrnaAdenine(58-N(1-Methyltransferase Catalytic Subunit Trmt61aMrna Methyladenosine-N(1-Methyltransferase Catalytic Subunit Trmt61aTrna(M1a58-Methyltransferase Subunit Trmt61aTrna(M1a58mtase Subunit Trmt61a |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Adenine(58-N(1-Methyltransferase Catalytic Subunit Trmt61a antibodyAnti-Mrna Methyladenosine-N(1-Methyltransferase Catalytic Subunit Trmt61a antibodyAnti-Trna(M1a58-Methyltransferase Subunit Trmt61a antibodyAnti-Trna(M1a58mtase Subunit Trmt61a antibodyAnti-TRMT61A antibodyAnti-C14orf172 antibodyAnti-TRM61 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
