Western blot analysis of various lysates using T <br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. <br/>Lysates/proteins: 25 Mu g per lane. <br/>Blocking buffer: 3% nonfat dry milk in TBST. <br/>Detection: ECL Basic Kit <br/>Exposure time: 10s.

Anti-TRMT6 antibody (1-200) (STJ113624)

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STJ113624
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRMT6
Gene ID: 51605
Uniprot ID: TRM6_HUMAN
Immunogen Region: 1-200
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human TRMT6 (NP_057023.2).
Immunogen Sequence: MEGSGEQPGPQPQHPGDHRI RDGDFVVLKREDVFKAVQVQ RRKKVTFEKQWFYLDNVIGH SYGTAFEVTSGGSLQPKKKR EEPTAETKEAGTDNRNIVDD GKSQKLTQDDIKALKDKGIK GEEIVQQLIENSTTFRDKTE FAQDKYIKKKKKKYEAIITV VKPSTRILSIMYYAREPGKI NHMRYDTLAQMLTLGNIRAG
Tissue Specificity Expressed in brain, liver, testis and ovary.
Function Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.
Protein Name Trna
Adenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6
Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6
Trna(M1a58-Methyltransferase Subunit Trm6
Trna(M1a58mtase Subunit Trm6
Database Links Reactome: R-HSA-6782315
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Trna antibody
Anti-Adenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibody
Anti-Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibody
Anti-Trna(M1a58-Methyltransferase Subunit Trm6 antibody
Anti-Trna(M1a58mtase Subunit Trm6 antibody
Anti-TRMT6 antibody
Anti-KIAA1153 antibody
Anti-TRM6 antibody
Anti-CGI-09 antibody

Information sourced from Uniprot.org

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