| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TOMM34 |
| Gene ID: | 10953 |
| Uniprot ID: | TOM34_HUMAN |
| Immunogen Region: | 1-309 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human TOMM34 (NP_006800.2). |
| Immunogen Sequence: | MAPKFPDSVEELRAAGNESF RNGQYAEASALYGRALRVLQ AQGSSDPEEESVLYSNRAAC HLKDGNCRDCIKDCTSALAL VPFSIKPLLRRASAYEALEK YPMAYVDYKTVLQIDDNVTS AVEGINRMTRALMDSLGPEW RLKLPSIPLVPVSAQKRWNS LPSENHKEMAKSKSKETTAT KNRVPSAGDVEKARVLKEEG NELVKKGNHKKAIEKYSESL LCSNLESATYSNRALCYLV |
| Tissue Specificity | Ubiquitous. |
| Function | Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state. |
| Protein Name | Mitochondrial Import Receptor Subunit Tom34Htom34Translocase Of Outer Membrane 34 Kda Subunit |
| Cellular Localisation | CytoplasmMitochondrion Outer MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Mitochondrial Import Receptor Subunit Tom34 antibodyAnti-Htom34 antibodyAnti-Translocase Of Outer Membrane 34 Kda Subunit antibodyAnti-TOMM34 antibodyAnti-URCC3 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and TOMM34 knockout (KO) HeLa cells, using [KO Validated] TOMM34 Rabbit polyclonal antibody (STJ11100836) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89771/358243/STJ11100836_1__34745.1713122577.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TOMM34 knockout (KO) HeLa cells, using [KO Validated] TOMM34 Rabbit polyclonal antibody (STJ11100836) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
