| Short Description : | Rabbit monoclonal TOMM22 (1-100) antibody for use in WB, IHC-P, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IP/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S2MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:100-1:1000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirement |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TOMM22 |
| Gene ID: | 56993 |
| Uniprot ID: | TOM22_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MAAAVAAAGAGEPQSPDELL PKGDAEKPEEELEEDDDEEL DETLSERLWGLTEMFPERVR SAAGATFDLSLFVAQKMYRF SRAALWIGTTSFMILVLPVV |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TOMM22 (Q9NS69). |
| Tissue Specificity | Ubiquitous. |
| Function | Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases. |
| Protein Name | Mitochondrial Import Receptor Subunit Tom22 HomologHtom221c9-2Translocase Of Outer Membrane 22 Kda Subunit Homolog |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-5205685 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Receptor Subunit Tom22 Homolog antibodyAnti-Htom22 antibodyAnti-1c9-2 antibodyAnti-Translocase Of Outer Membrane 22 Kda Subunit Homolog antibodyAnti-TOMM22 antibodyAnti-TOM22 antibody |
Information sourced from Uniprot.org
