Anti-TOM1L2 antibody (310-450) (STJ11103386)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TOM1L2 (310-450) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TOM1L2 |
| Gene ID | 146691 |
| Uniprot ID | TM1L2_HUMAN |
| Immunogen Region | 310-450 |
| Immunogen Sequence | SGRSVQNASNGVLNEVTEDN LIDLGPGSPAVVSPMVGNTA PPSSLSSQLAGLDLGTESVS GTLSSLQQCNPRDGFDMFAQ TRGNSLAEQRKTVTYEDPQA VGGLASALDNRKQSSEGIPV AQPSVMDDIEVWLRTDLKGD D |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 310-450 of human TOM1L2 (NP_001076437.1). |
Additional Info
| Tissue Specificity | Ubiquitously expressed with higher expression in heart and skeletal muscle. |
| Function | Acts as a MYO6/Myosin VI adapter protein that targets myosin VI to endocytic structures. May also play a role in recruiting clathrin to endosomes. May regulate growth factor-induced mitogenic signaling. |
| Protein Name | Tom1-Like Protein 2Target Of Myb-Like Protein 2 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tom1-Like Protein 2 antibodyAnti-Target Of Myb-Like Protein 2 antibodyAnti-TOM1L2 antibody |
Information sourced from Uniprot.org